> If they are known to cause retardation, then they are known to have impact on cognition. That statement was intentionally framed as neutrally as possible.
And there is a difference between an allele present in the majority of the population which lowers the IQ and one which is present in a minority and raises IQ. A Mendelian mutation in <1% of the population which lowers your IQ by 10 points is not the same thing as a mutation which raises your IQ by 10 points. The former certainly do exist. The latter currently do not.
> I'm currently failing to find the source I know I saw not terribly long ago linking some genetic disorder to higher IQs and to altered brain stuff of some sort. I don't have the time to keep digging for it.
I'll give you a hint, you won't find it, and if you do, it'll be a candidate-gene paper from the '00s where the p-values are just barely south of 0.05, not remotely close to genome-wide statistical-significance, and has never been validated since even in the exome GWASes which should have found it.
> But, here's a study of people with CF -- a common genetic disorder in the Jewish community -- that says, in essence "Lower IQ scores in this population can be linked to negative health impacts and other negative factors," yet seems to list the average IQ for this group of 89 very, very, deathly ill patients as 102.5. Which sort of implies to me that if they weren't basically dying from their disorder, they would be far above average intelligence.
You know who else has above average intelligence? Ashkenazi Jews. Including the ones without CF. And it's higher than 102.5.
And there is a difference between an allele present in the majority of the population which lowers the IQ and one which is present in a minority and raises IQ. A Mendelian mutation in <1% of the population which lowers your IQ by 10 points is not the same thing as a mutation which raises your IQ by 10 points. The former certainly do exist. The latter currently do not.
> I'm currently failing to find the source I know I saw not terribly long ago linking some genetic disorder to higher IQs and to altered brain stuff of some sort. I don't have the time to keep digging for it.
I'll give you a hint, you won't find it, and if you do, it'll be a candidate-gene paper from the '00s where the p-values are just barely south of 0.05, not remotely close to genome-wide statistical-significance, and has never been validated since even in the exome GWASes which should have found it.
> But, here's a study of people with CF -- a common genetic disorder in the Jewish community -- that says, in essence "Lower IQ scores in this population can be linked to negative health impacts and other negative factors," yet seems to list the average IQ for this group of 89 very, very, deathly ill patients as 102.5. Which sort of implies to me that if they weren't basically dying from their disorder, they would be far above average intelligence.
You know who else has above average intelligence? Ashkenazi Jews. Including the ones without CF. And it's higher than 102.5.