Maybe not. I've already spent $20-30 on iPad audio books for my son, they highlight the words as they are read, he loves them. iPad is his favorite toy, unfortunately, I've found out: I bought him a Stinky the Garbage Truck for $50that he's been talking about and he still wants to play with the iPad. And he's 4!
CD-ROMs are physical, you have to buy them in a store or order them from somewhere, you have to put them in those huge, bulky computers and sit in front of them.
I see few, if any, points of comparison. Magazines and books on tablets might still fail but I fail to see how comparisons to CD-ROM publishing are useful.