One of the things that interested me the most about this article was the unintended consequences of various measures used to gauge progress.

For example, researchers seem to be evaluated by the number of papers written, number of publications and peer acknowledgement. These metrics favor the mouse model heavily, with its cheap and fast methodology. It also seems to promote behaviors that seem at odds with what should arguably be the end goal of the work: creating working drugs.

It paints a rather bleak picture of the establishment with that goal in mind, despite the best intentions.